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Optimizing the phenotyping of rodent ASD models: enrichment analysis of mouse and human neurobiological phenotypes associated with high-risk autism genes identifies morphological, electrophysiological, neurological, and behavioral features

BACKGROUND: There is interest in defining mouse neurobiological phenotypes useful for studying autism spectrum disorders (ASD) in both forward and reverse genetic approaches. A recurrent focus has been on high-order behavioral analyses, including learning and memory paradigms and social paradigms. H...

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Detalles Bibliográficos
Autores principales: Buxbaum, Joseph D, Betancur, Catalina, Bozdagi, Ozlem, Dorr, Nate P, Elder, Gregory A, Hof, Patrick R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337792/
https://www.ncbi.nlm.nih.gov/pubmed/22348382
http://dx.doi.org/10.1186/2040-2392-3-1