Scavenging of CXCL12 by CXCR7 Promotes Tumor Growth and Metastasis of CXCR4-positive Breast Cancer Cells

Chemokine CXCL12 and receptor CXCR4 control multiple steps in primary tumor growth and metastasis in breast cancer and more than 20 other human malignancies. Mechanisms that regulate availability of CXCL12 in tumor microenvironments will substantially impact cancer progression and ongoing efforts to...

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Detalles Bibliográficos
Autores principales: Luker, Kathryn E., Lewin, Sarah A., Mihalko, Laura Anne, Schmidt, Bradley T., Winkler, Jessica S., Coggins, Nathaniel L., Thomas, Dafydd G., Luker, Gary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337948/
https://www.ncbi.nlm.nih.gov/pubmed/22266857
http://dx.doi.org/10.1038/onc.2011.633

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