A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

Cell-type-specific expression of optogenetic molecules allows temporally precise manipulation of targeted neuronal activity. Here we present a toolbox of 4 knock-in mouse lines engineered for strong, Cre-dependent expression of channelrhodopsins ChR2-tdTomato and ChR2-EYFP, halorhodopsin eNpHR3.0, a...

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Detalles Bibliográficos
Autores principales: Madisen, Linda, Mao, Tianyi, Koch, Henner, Zhuo, Jia-min, Berenyi, Antal, Fujisawa, Shigeyoshi, Hsu, Yun-Wei A., Garcia, Alfredo J., Gu, Xuan, Zanella, Sebastien, Kidney, Jolene, Gu, Hong, Mao, Yimei, Hooks, Bryan M., Boyden, Edward S., Buzsáki, György, Ramirez, Jan Marino, Jones, Allan R., Svoboda, Karel, Han, Xue, Turner, Eric E., Zeng, Hongkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337962/
https://www.ncbi.nlm.nih.gov/pubmed/22446880
http://dx.doi.org/10.1038/nn.3078

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