Cargando…
VAMP4 directs synaptic vesicles to a pool that selectively maintains asynchronous neurotransmission
Synaptic vesicles in the brain harbor several SNARE proteins. With the exception of synaptobrevin2/VAMP2 (syb2) that is directly involved in vesicle fusion, the role of these SNAREs in neurotransmission is unclear. Here, we show that in mice while syb2 drives rapid Ca(2+)-dependent synchronous neuro...
Autores principales: | Raingo, Jesica, Khvotchev, Mikhail, Liu, Pei, Darios, Frederic, Li, Ying C., Ramirez, Denise M.O., Adachi, Megumi, Lemieux, Philippe, Toth, Katalin, Davletov, Bazbek, Kavalali, Ege T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337975/ https://www.ncbi.nlm.nih.gov/pubmed/22406549 http://dx.doi.org/10.1038/nn.3067 |
Ejemplares similares
-
Spontaneous neurotransmission signals through store-driven Ca(2+) transients to maintain synaptic homeostasis
por: Reese, Austin L, et al.
Publicado: (2015) -
Sphingosine Facilitates SNARE Complex Assembly and Activates Synaptic Vesicle Exocytosis
por: Darios, Frédéric, et al.
Publicado: (2009) -
Selective molecular impairment of spontaneous neurotransmission modulates synaptic efficacy
por: Crawford, Devon C., et al.
Publicado: (2017) -
Nano-Organization at the Synapse: Segregation of Distinct Forms of Neurotransmission
por: Guzikowski, Natalie J., et al.
Publicado: (2021) -
Single synapse evaluation of the postsynaptic NMDA receptors targeted by evoked and spontaneous neurotransmission
por: Reese, Austin L, et al.
Publicado: (2016)