Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons

Human acute and inflammatory pain requires the expression of voltage-gated sodium channel Nav1.7 but its significance for neuropathic pain is unknown. Here we show that Nav1.7 expression in different sets of mouse sensory and sympathetic neurons underlies distinct types of pain sensation. Ablating N...

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Detalles Bibliográficos
Autores principales: Minett, Michael S., Nassar, Mohammed A., Clark, Anna K., Passmore, Gayle, Dickenson, Anthony H., Wang, Fan, Malcangio, Marzia, Wood, John N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337979/
https://www.ncbi.nlm.nih.gov/pubmed/22531176
http://dx.doi.org/10.1038/ncomms1795

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