Cargando…

An integrated analysis of miRNA and gene copy numbers in xenografts of Ewing's sarcoma

BACKGROUND: Xenografts have been shown to provide a suitable source of tumor tissue for molecular analysis in the absence of primary tumor material. We utilized ES xenograft series for integrated microarray analyses to identify novel biomarkers. METHOD: Microarray technology (array comparative genom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mosakhani, Neda, Guled, Mohamed, Leen, Gayle, Calabuig-Fariñas, Silvia, Niini, Tarja, Machado, Isidro, Savola, Suvi, Scotlandi, Katia, López-Guerrero, José Antonio, Llombart-Bosch, Antonio, Knuutila, Sakari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338077/ https://www.ncbi.nlm.nih.gov/pubmed/22429812 http://dx.doi.org/10.1186/1756-9966-31-24

Ejemplares similares

Combined use of expression and CGH arrays pinpoints novel candidate genes in Ewing sarcoma family of tumors
por: Savola, Suvi, et al.
Publicado: (2009)

High Expression of Complement Component 5 (C5) at Tumor Site Associates with Superior Survival in Ewing's Sarcoma Family of Tumour Patients
por: Savola, Suvi, et al.
Publicado: (2011)

Down-regulation of miR-181c in imatinib-resistant chronic myeloid leukemia
por: Mosakhani, Neda, et al.
Publicado: (2013)

Tissue microarrays analysis in chondrosarcomas: light microscopy, immunohistochemistry and xenograft study
por: Machado, Isidro, et al.
Publicado: (2008)

Tissue microarrays: applications in study of p16 and p53 alterations in Ewing's cell lines
por: Noguera, Rosa, et al.
Publicado: (2008)

USP1 Expression Driven by EWS::FLI1 Transcription Factor Stabilizes Survivin and Mitigates Replication Stress in Ewing Sarcoma
por: Mallard, Halle J., et al.
Publicado: (2023)

High-risk gastrointestinal stromal tumour (GIST) and synovial sarcoma display similar angiogenic profiles: a nude mice xenograft study
por: Giner, Francisco, et al.
Publicado: (2017)

EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis
por: Chakraborty, Sukanya, et al.
Publicado: (2023)

Downregulation of Plasma MiR-142-3p and MiR-26a-5p in Patients With Colorectal Carcinoma
por: Ghanbari, Reza, et al.
Publicado: (2015)

Simultaneous Underexpression of let-7a-5p and let-7f-5p microRNAs in Plasma and Stool Samples from Early Stage Colorectal Carcinoma
por: Ghanbari, Reza, et al.
Publicado: (2016)

Classification of human cancers based on DNA copy number amplification modeling
por: Myllykangas, Samuel, et al.
Publicado: (2008)

Patient Derived Xenografts for Genome-Driven Therapy of Osteosarcoma
por: Landuzzi, Lorena, et al.
Publicado: (2021)

CanGEM: mining gene copy number changes in cancer
por: Scheinin, Ilari, et al.
Publicado: (2008)

Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma
por: García-Domínguez, Daniel J., et al.
Publicado: (2021)

Intimal Sarcoma with MDM2/CDK4 Amplification and p16 Overexpression: A Review of Histological Features in Primary Tumor and Xenograft, with Immunophenotype and Molecular Profiling
por: Giner, Francisco, et al.
Publicado: (2023)

Targeting ROCK2 rather than ROCK1 inhibits Ewing sarcoma malignancy
por: Pinca, Rosa Simona, et al.
Publicado: (2017)

Quantification of the Heterogeneity of Prognostic Cellular Biomarkers in Ewing Sarcoma Using Automated Image and Random Survival Forest Analysis
por: Bühnemann, Claudia, et al.
Publicado: (2014)

Copy Number Alterations and Methylation in Ewing's Sarcoma
por: Jahromi, Mona S., et al.
Publicado: (2011)

CGHpower: exploring sample size calculations for chromosomal copy number experiments
por: Scheinin, Ilari, et al.
Publicado: (2010)

The First European Interdisciplinary Ewing Sarcoma Research Summit
por: Kovar, Heinrich, et al.
Publicado: (2012)

mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts
por: Kuijjer, Marieke L, et al.
Publicado: (2011)

The CXCR4-CXCL12 axis in Ewing sarcoma: promotion of tumor growth rather than metastatic disease
por: Berghuis, Dagmar, et al.
Publicado: (2012)

Polymorphic variants of IGF2BP3 and SENCR have an impact on predisposition and/or progression of Ewing sarcoma
por: Martinelli, Marcella, et al.
Publicado: (2022)

Biomarker analysis in human neoplasias: superior next-generation sequencing on frozen bone marrow cells and on formalin-fixed, paraffin-embedded tumor tissues
por: Knuutila, Sakari
Publicado: (2013)

CD99 polymorphisms significantly influence the probability to develop Ewing sarcoma in earlier age and patient disease progression
por: Martinelli, Marcella, et al.
Publicado: (2016)

The Genomic Landscape of the Ewing Sarcoma Family of Tumors Reveals Recurrent STAG2 Mutation
por: Brohl, Andrew S., et al.
Publicado: (2014)

Lamin A and the LINC complex act as potential tumor suppressors in Ewing Sarcoma
por: Chiarini, Francesca, et al.
Publicado: (2022)

Exosomes from CD99-deprived Ewing sarcoma cells reverse tumor malignancy by inhibiting cell migration and promoting neural differentiation
por: De Feo, Alessandra, et al.
Publicado: (2019)

Clinical relevance of copy number profiling in oral and oropharyngeal squamous cell carcinoma
por: van Kempen, Pauline M W, et al.
Publicado: (2015)

Characterization of Human Mesenchymal Stem Cells from Ewing Sarcoma Patients. Pathogenetic Implications
por: Amaral, Ana Teresa, et al.
Publicado: (2014)

Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 Modulates Aggressiveness of Ewing Sarcoma by Regulating the CD164-CXCR4 Axis
por: Mancarella, Caterina, et al.
Publicado: (2020)

Prognostic impact of chromosomal aberrations in Ewing tumours
por: Hattinger, C M, et al.
Publicado: (2002)

miR-486-5p expression is regulated by DNA methylation in osteosarcoma
por: Namløs, Heidi M., et al.
Publicado: (2022)

Inhibition of porcupine prolongs metastasis free survival in a mouse xenograft model of Ewing sarcoma
por: Hayashi, Masanori, et al.
Publicado: (2017)

Solitary Fibrous Tumor: Integration of Clinical, Morphologic, Immunohistochemical and Molecular Findings in Risk Stratification and Classification May Better Predict Patient outcome
por: Machado, Isidro, et al.
Publicado: (2021)

miR-214-3p Is Commonly Downregulated by EWS-FLI1 and by CD99 and Its Restoration Limits Ewing Sarcoma Aggressiveness
por: De Feo, Alessandra, et al.
Publicado: (2022)

CD99 triggering induces methuosis of Ewing sarcoma cells through IGF-1R/RAS/Rac1 signaling
por: Manara, Maria Cristina, et al.
Publicado: (2016)

N-(4-Hydroxyphenyl) Retinamide Potentiated Anti-Tumor Efficacy of Genistein in Human Ewing’s Sarcoma Xenografts
por: Karmakar, Surajit, et al.
Publicado: (2011)

Quantitative copy number analysis by Multiplex Ligation-dependent Probe Amplification (MLPA) of BRCA1-associated breast cancer regions identifies BRCAness
por: Lips, Esther H, et al.
Publicado: (2011)

Establishment and characterization of in vivo orthotopic bioluminescent xenograft models from human osteosarcoma cell lines in Swiss nude and NSG mice
por: Marques da Costa, Maria Eugenia, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_a90ria0f8po3lsvdado3pbdtqd