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NF-κB as potential target in the treatment of melanoma
The RAS/MAP kinase pathway has attracted attention because activating mutations of the BRAF serine/threonine kinase was described in over 50% of melanomas. Very recently, selective and potent BRAF inhibitors have been developed. Several other signal transduction pathways have been found to be consti...
Autores principales: | Madonna, Gabriele, Ullman, Claudio Dansky, Gentilcore, Giusy, Palmieri, Giuseppe, Ascierto, Paolo Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338086/ https://www.ncbi.nlm.nih.gov/pubmed/22433222 http://dx.doi.org/10.1186/1479-5876-10-53 |
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