Cargando…
Cyclic intensive light exposure induces retinal lesions similar to age-related macular degeneration in APPswe/PS1 bigenic mice
BACKGROUND: Intensive light exposure and beta-amyloid (Aβ) aggregates have been known as a risk factor for macular degeneration and an important component in the pathologic drusen structure involved in this disorder, respectively. However, it is unknown whether Aβ deposition mediates or exacerbates...
Autores principales: | Dong, Zhizhang, Li, Juan, Leng, Yunxia, Sun, Xuerong, Hu, Huiling, He, Yuan, Tan, Zhiqun, Ge, Jian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338397/ https://www.ncbi.nlm.nih.gov/pubmed/22443196 http://dx.doi.org/10.1186/1471-2202-13-34 |
Ejemplares similares
-
Suppressed Retinal Degeneration in Aged Wild Type and APPswe/PS1ΔE9 Mice by Bone Marrow Transplantation
por: Yang, Yue, et al.
Publicado: (2013) -
TDP-43 promotes tau accumulation and selective neurotoxicity in bigenic Caenorhabditis elegans
por: Latimer, Caitlin S., et al.
Publicado: (2022) -
Characterization and retinal neuron differentiation of WERI-Rb1 cancer stem cells
por: Hu, Huiling, et al.
Publicado: (2012) -
Amyloid Structural Changes Studied by Infrared Microspectroscopy in Bigenic Cellular Models of Alzheimer’s Disease
por: Paulus, Agnes, et al.
Publicado: (2021) -
Mevalonate kinase somatic mosaicism and bigenic genotypes may explain heterogeneity in mevalonate kinase deficiency
por: Shinar, Y, et al.
Publicado: (2015)