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Gcn5p-dependent acetylation induces degradation of the meiotic transcriptional repressor Ume6p

Ume6p represses early meiotic gene transcription in Saccharomyces cerevisiae by recruiting the Rpd3p histone deacetylase and chromatin-remodeling proteins. Ume6p repression is relieved in a two-step destruction process mediated by the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Th...

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Detalles Bibliográficos
Autores principales:	Mallory, Michael J., Law, Michael J., Sterner, David E., Berger, Shelley L., Strich, Randy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338428/ https://www.ncbi.nlm.nih.gov/pubmed/22438583 http://dx.doi.org/10.1091/mbc.E11-06-0536

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