Cargando…

Biogenesis of the preprotein translocase of the outer mitochondrial membrane: protein kinase A phosphorylates the precursor of Tom40 and impairs its import

The preprotein translocase of the outer mitochondrial membrane (TOM) functions as the main entry gate for the import of nuclear-encoded proteins into mitochondria. The major subunits of the TOM complex are the three receptors Tom20, Tom22, and Tom70 and the central channel-forming protein Tom40. Cyt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rao, Sanjana, Schmidt, Oliver, Harbauer, Angelika B., Schönfisch, Birgit, Guiard, Bernard, Pfanner, Nikolaus, Meisinger, Chris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338429/ https://www.ncbi.nlm.nih.gov/pubmed/22419819 http://dx.doi.org/10.1091/mbc.E11-11-0933

Ejemplares similares

Alternative function for the mitochondrial SAM complex in biogenesis of α-helical TOM proteins
por: Stojanovski, Diana, et al.
Publicado: (2007)

Alternative function for the mitochondrial SAM complex in biogenesis of α-helical TOM proteins
por: Stojanovski, Diana, et al.
Publicado: (2007)

Assembly of the Mitochondrial Protein Import Channel: Role of Tom5 in Two-Stage Interaction of Tom40 with the SAM Complex
por: Becker, Thomas, et al.
Publicado: (2010)

Two conformations of the Tom20 preprotein receptor in the TOM holo complex
por: Ornelas, Pamela, et al.
Publicado: (2023)

Biogenesis of Porin of the Outer Mitochondrial Membrane Involves an Import Pathway via Receptors and the General Import Pore of the Tom Complex
por: Krimmer, Thomas, et al.
Publicado: (2001)

Cooperation of translocase complexes in mitochondrial protein import
por: Kutik, Stephan, et al.
Publicado: (2007)

The preprotein translocase YidC controls respiratory metabolism in Mycobacterium tuberculosis
por: Thakur, Preeti, et al.
Publicado: (2016)

Preprotein mature domains contain translocase targeting signals that are essential for secretion
por: Chatzi, Katerina E., et al.
Publicado: (2017)

Translocase of the Outer Mitochondrial Membrane 40 Is Required for Mitochondrial Biogenesis and Embryo Development in Arabidopsis
por: Hu, Ying, et al.
Publicado: (2019)

A First Glimpse at the Structure of the Tom Translocase from the Mitochondrial Outer Membrane
por: Verschoor, Adriana, et al.
Publicado: (1999)

Biogenesis of Tom40, Core Component of the Tom Complex of Mitochondria
por: Rapaport, Doron, et al.
Publicado: (1999)

The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins
por: Becker, Thomas, et al.
Publicado: (2011)

Biogenesis of mitochondrial β-barrel proteins: the POTRA domain is involved in precursor release from the SAM complex
por: Stroud, David A., et al.
Publicado: (2011)

Tom70 enhances mitochondrial preprotein import efficiency by binding to internal targeting sequences
por: Backes, Sandra, et al.
Publicado: (2018)

Recruitment of Cytosolic J-Proteins by TOM Receptors Promotes Mitochondrial Protein Biogenesis
por: Opaliński, Łukasz, et al.
Publicado: (2018)

AIP is a mitochondrial import mediator that binds to both import receptor Tom20 and preproteins
por: Yano, Masato, et al.
Publicado: (2003)

The Pro-Apoptotic BH3-Only Protein Bim Interacts with Components of the Translocase of the Outer Mitochondrial Membrane (TOM)
por: Frank, Daniel O., et al.
Publicado: (2015)

A J-protein is an essential subunit of the presequence translocase–associated protein import motor of mitochondria
por: Truscott, Kaye N., et al.
Publicado: (2003)

Tom40, the Pore-Forming Component of the Protein-Conducting Tom Channel in the Outer Membrane of Mitochondria
por: Ahting, Uwe, et al.
Publicado: (2001)

Structural insights into assembly of human mitochondrial translocase TOM complex
por: Guan, Zeyuan, et al.
Publicado: (2021)

Mitochondrial OXA Translocase Plays a Major Role in Biogenesis of Inner-Membrane Proteins
por: Stiller, Sebastian B., et al.
Publicado: (2016)

Sam37 is crucial for formation of the mitochondrial TOM–SAM supercomplex, thereby promoting β-barrel biogenesis
por: Wenz, Lena-Sophie, et al.
Publicado: (2015)

How does the TOM complex mediate insertion of precursor proteins into the mitochondrial outer membrane?
por: Rapaport, Doron
Publicado: (2005)

Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes
por: Gebert, Michael, et al.
Publicado: (2012)

Metabolic Regulation of Mitochondrial Protein Biogenesis from a Neuronal Perspective
por: Hees, Jara Tabitha, et al.
Publicado: (2022)

Sorting switch of mitochondrial presequence translocase involves coupling of motor module to respiratory chain
por: Wiedemann, Nils, et al.
Publicado: (2007)

Structural overview of the translocase of the mitochondrial outer membrane complex
por: Araiso, Yuhei, et al.
Publicado: (2022)

Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization
por: Vögtle, F.-Nora, et al.
Publicado: (2011)

The journey of preproteins across the chloroplast membrane systems
por: Ballabani, Gent, et al.
Publicado: (2023)

The targeting of the atToc159 preprotein receptor to the chloroplast outer membrane is mediated by its GTPase domain and is regulated by GTP
por: Smith, Matthew D., et al.
Publicado: (2002)

Tom70-based transcriptional regulation of mitochondrial biogenesis and aging
por: Liu, Qingqing, et al.
Publicado: (2022)

Characterization of the Signal That Directs Tom20 to the Mitochondrial Outer Membrane
por: Kanaji, Sachiko, et al.
Publicado: (2000)

Protein folding causes an arrest of preprotein translocation into mitochondria in vivo
Publicado: (1991)

Dimeric SecA Couples the Preprotein Translocation in an Asymmetric Manner
por: Tang, Ying, et al.
Publicado: (2011)

Structure of the SecY Complex Unlocked by a Preprotein Mimic
por: Hizlan, Dilem, et al.
Publicado: (2012)

Mitochondrial protein import: precursor oxidation in a ternary complex with disulfide carrier and sulfhydryl oxidase
por: Stojanovski, Diana, et al.
Publicado: (2008)

Role of mitochondrial inner membrane organizing system in protein biogenesis of the mitochondrial outer membrane
por: Bohnert, Maria, et al.
Publicado: (2012)

The role of GTP binding and hydrolysis at the atToc159 preprotein receptor during protein import into chloroplasts
por: Wang, Fei, et al.
Publicado: (2008)

Mitochondrial protein translocation machinery: From TOM structural biogenesis to functional regulation
por: Sayyed, Ulfat Mohd. Hanif, et al.
Publicado: (2022)

In vitro uptake and processing of prezein and other maize preproteins by maize membranes
Publicado: (1981)

Cannot write session to /tmp/vufind_sessions/sess_5uo23m8ahap8hhjrs8dqebtlem