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Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila

Bidirectional axonal transport driven by kinesin and dynein along microtubules is critical to neuronal viability and function. To evaluate axonal transport mechanisms, we developed a high-resolution imaging system to track the movement of amyloid precursor protein (APP) vesicles in Drosophila segmen...

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Detalles Bibliográficos
Autores principales: Reis, Gerald F., Yang, Ge, Szpankowski, Lukasz, Weaver, Carole, Shah, Sameer B., Robinson, John T., Hays, Thomas S., Danuser, Gaudenz, Goldstein, Lawrence S. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338437/
https://www.ncbi.nlm.nih.gov/pubmed/22398725
http://dx.doi.org/10.1091/mbc.E11-11-0938