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Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila
Bidirectional axonal transport driven by kinesin and dynein along microtubules is critical to neuronal viability and function. To evaluate axonal transport mechanisms, we developed a high-resolution imaging system to track the movement of amyloid precursor protein (APP) vesicles in Drosophila segmen...
Autores principales: | Reis, Gerald F., Yang, Ge, Szpankowski, Lukasz, Weaver, Carole, Shah, Sameer B., Robinson, John T., Hays, Thomas S., Danuser, Gaudenz, Goldstein, Lawrence S. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338437/ https://www.ncbi.nlm.nih.gov/pubmed/22398725 http://dx.doi.org/10.1091/mbc.E11-11-0938 |
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