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Tau-Mediated Nuclear Depletion and Cytoplasmic Accumulation of SFPQ in Alzheimer's and Pick's Disease
Tau dysfunction characterizes neurodegenerative diseases such as Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD). Here, we performed an unbiased SAGE (serial analysis of gene expression) of differentially expressed mRNAs in the amygdala of transgenic pR5 mice that express...
Autores principales: | Ke, Yazi, Dramiga, Joe, Schütz, Ulrich, Kril, Jillian J., Ittner, Lars M., Schröder, Hannsjörg, Götz, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338448/ https://www.ncbi.nlm.nih.gov/pubmed/22558197 http://dx.doi.org/10.1371/journal.pone.0035678 |
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