Assessment of Pseudomonas aeruginosa N (5),N (10)-Methylenetetrahydrofolate Dehydrogenase - Cyclohydrolase as a Potential Antibacterial Drug Target

The bifunctional enzyme methylenetetrahydrofolate dehydrogenase – cyclohydrolase (FolD) is identified as a potential drug target in Gram-negative bacteria, in particular the troublesome Pseudomonas aeruginosa. In order to provide a comprehensive and realistic assessment of the potential of this targ...

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Detalles Bibliográficos
Autores principales: Eadsforth, Thomas C., Gardiner, Mary, Maluf, Fernando V., McElroy, Stuart, James, Daniel, Frearson, Julie, Gray, David, Hunter, William N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338484/
https://www.ncbi.nlm.nih.gov/pubmed/22558288
http://dx.doi.org/10.1371/journal.pone.0035973

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