Hematopoietic miR155 Deficiency Enhances Atherosclerosis and Decreases Plaque Stability in Hyperlipidemic Mice

microRNA-155 (miR155) is a central regulator of immune responses that is induced by inflammatory mediators. Although miR155 is considered to be a pro-inflammatory microRNA, in vitro reports show anti-inflammatory effects in lipid-loaded cells. In this study we examined the role of miR155 in atherosc...

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Detalles Bibliográficos
Autores principales: Donners, Marjo M. P. C., Wolfs, Ine M. J., Stöger, Lauran J., van der Vorst, Emiel P. C., Pöttgens, Chantal C. H., Heymans, Stephane, Schroen, Blanche, Gijbels, Marion J. J., de Winther, Menno P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338496/
https://www.ncbi.nlm.nih.gov/pubmed/22558252
http://dx.doi.org/10.1371/journal.pone.0035877

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