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Translation Levels Control Multi-Spanning Membrane Protein Expression

Attempts to express eukaryotic multi-spanning membrane proteins at high-levels have been generally unsuccessful. In order to investigate the cause of this limitation and gain insight into the rate limiting processes involved, we have analyzed the effect of translation levels on the expression of sev...

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Detalles Bibliográficos
Autores principales: Kim, Hok Seon, Ernst, James A., Brown, Cecilia, Bostrom, Jenny, Fuh, Germaine, Lee, Chingwei V., Huang, Arthur, Vandlen, Richard L., Yansura, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338534/
https://www.ncbi.nlm.nih.gov/pubmed/22563408
http://dx.doi.org/10.1371/journal.pone.0035844