Cargando…
Lipopolysaccharide Induces Lung Fibroblast Proliferation through Toll-Like Receptor 4 Signaling and the Phosphoinositide3-Kinase-Akt Pathway
Pulmonary fibrosis is characterized by lung fibroblast proliferation and collagen secretion. In lipopolysaccharide (LPS)-induced acute lung injury (ALI), aberrant proliferation of lung fibroblasts is initiated in early disease stages, but the underlying mechanism remains unknown. In this study, we k...
Autores principales: | He, Zhengyu, Gao, Yuan, Deng, Yuxiao, Li, Wen, Chen, Yongming, Xing, Shunpeng, Zhao, Xianyuan, Ding, Jia, Wang, Xiangrui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338545/ https://www.ncbi.nlm.nih.gov/pubmed/22563417 http://dx.doi.org/10.1371/journal.pone.0035926 |
Ejemplares similares
-
Overexpression of PTEN suppresses lipopolysaccharide-induced lung fibroblast proliferation, differentiation and collagen secretion through inhibition of the PI3-K-Akt-GSK3beta pathway
por: He, Zhengyu, et al.
Publicado: (2014) -
Epigenetic regulation of Thy-1 gene expression by histone modification is involved in lipopolysaccharide-induced lung fibroblast proliferation
por: He, Zhengyu, et al.
Publicado: (2013) -
Thy-1 depletion and integrin β3 upregulation-mediated PI3K-Akt-mTOR pathway activation inhibits lung fibroblast autophagy in lipopolysaccharide-induced pulmonary fibrosis
por: Wan, Hanxi, et al.
Publicado: (2019) -
Phosphoinositide turnover in Toll-like receptor signaling and trafficking
por: Tu Le, Oanh Thi, et al.
Publicado: (2014) -
Toll-Like Receptor 4 Mediates Acute Lung Injury Induced by High Mobility Group Box-1
por: Deng, Yuxiao, et al.
Publicado: (2013)