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Securin Enhances the Anti-Cancer Effects of 6-Methoxy-3-(3′,4′,5′-Trimethoxy-Benzoyl)-1H-Indole (BPR0L075) in Human Colorectal Cancer Cells

BPR0L075 [6-methoxy-3-(3′,4′,5′-trimethoxy-benzoyl)-1H-indole] is a novel anti-microtubule drug with anti-tumor and anti-angiogenic activities in vitro and in vivo. Securin is required for genome stability, and is expressed abundantly in most cancer cells, promoting cell proliferation and tumorigene...

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Detalles Bibliográficos
Autores principales:	Tseng, Ho-Hsing, Chuah, Qiu-Yu, Yang, Pei-Ming, Chen, Chiung-Tong, Chao, Jung-Chi, Lin, Ming-Der, Chiu, Shu-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338557/ https://www.ncbi.nlm.nih.gov/pubmed/22563433 http://dx.doi.org/10.1371/journal.pone.0036006

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