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Soluble Immune Complexes Shift the TLR-Induced Cytokine Production of Distinct Polarized Human Macrophage Subsets towards IL-10

BACKGROUND: Costimulation of murine macrophages with immune complexes (ICs) and TLR ligands leads to alternative activation. Studies on human myeloid cells, however, indicate that ICs induce an increased pro-inflammatory cytokine production. This study aimed to clarify the effect of ICs on the pro-...

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Detalles Bibliográficos
Autores principales:	Ambarus, Carmen A., Santegoets, Kim C. M., van Bon, Lenny, Wenink, Mark H., Tak, Paul P., Radstake, Timothy R. D. J., Baeten, Dominique L. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338562/ https://www.ncbi.nlm.nih.gov/pubmed/22563430 http://dx.doi.org/10.1371/journal.pone.0035994

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