Features of Idebenone and Related Short-Chain Quinones that Rescue ATP Levels under Conditions of Impaired Mitochondrial Complex I

Short-chain quinones have been investigated as therapeutic molecules due to their ability to modulate cellular redox reactions, mitochondrial electron transfer and oxidative stress, which are pathologically altered in many mitochondrial and neuromuscular disorders. Recently, we and others described...

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Detalles Bibliográficos
Autores principales: Erb, Michael, Hoffmann-Enger, Barbara, Deppe, Holger, Soeberdt, Michael, Haefeli, Roman H., Rummey, Christian, Feurer, Achim, Gueven, Nuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338594/
https://www.ncbi.nlm.nih.gov/pubmed/22558363
http://dx.doi.org/10.1371/journal.pone.0036153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338594/
https://www.ncbi.nlm.nih.gov/pubmed/22558363
http://dx.doi.org/10.1371/journal.pone.0036153

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