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Altered Prion Protein Expression Pattern in CSF as a Biomarker for Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob disease (CJD) is the most frequent human Prion-related disorder (PrD). The detection of 14-3-3 protein in the cerebrospinal fluid (CSF) is used as a molecular diagnostic criterion for patients clinically compatible with CJD. However, there is a pressing need for the identification...

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Detalles Bibliográficos
Autores principales: Torres, Mauricio, Cartier, Luis, Matamala, José Manuel, Hernández, Nancy, Woehlbier, Ute, Hetz, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338608/
https://www.ncbi.nlm.nih.gov/pubmed/22558368
http://dx.doi.org/10.1371/journal.pone.0036159