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The Insulin Receptor Substrate 1 (Irs1) in Intestinal Epithelial Differentiation and in Colorectal Cancer

Colorectal cancer (CRC) is associated with lifestyle factors that affect insulin/IGF signaling, of which the insulin receptor substrate 1 (IRS1) is a key transducer. We investigated expression, localization and pathologic correlations of IRS1 in cancer-uninvolved colonic epithelium, primary CRCs wit...

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Detalles Bibliográficos
Autores principales:	Esposito, Diana L., Aru, Federica, Lattanzio, Rossano, Morgano, Annalisa, Abbondanza, Michela, Malekzadeh, Reza, Bishehsari, Faraz, Valanzano, Rosa, Russo, Antonio, Piantelli, Mauro, Moschetta, Antonio, Lotti, Lavinia Vittoria, Mariani-Costantini, Renato
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338610/ https://www.ncbi.nlm.nih.gov/pubmed/22558377 http://dx.doi.org/10.1371/journal.pone.0036190

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