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Linking Yeast Gcn5p Catalytic Function and Gene Regulation Using a Quantitative, Graded Dominant Mutant Approach

Establishing causative links between protein functional domains and global gene regulation is critical for advancements in genetics, biotechnology, disease treatment, and systems biology. This task is challenging for multifunctional proteins when relying on traditional approaches such as gene deleti...

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Detalles Bibliográficos
Autores principales: Lanza, Amanda M., Blazeck, John J., Crook, Nathan C., Alper, Hal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338614/
https://www.ncbi.nlm.nih.gov/pubmed/22558379
http://dx.doi.org/10.1371/journal.pone.0036193

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