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Ligand Binding Study of Human PEBP1/RKIP: Interaction with Nucleotides and Raf-1 Peptides Evidenced by NMR and Mass Spectrometry
BACKGROUND: Human Phosphatidylethanolamine binding protein 1 (hPEBP1) also known as Raf kinase inhibitory protein (RKIP), affects various cellular processes, and is implicated in metastasis formation and Alzheimer's disease. Human PEBP1 has also been shown to inhibit the Raf/MEK/ERK pathway. Nu...
Autores principales: | Tavel, Laurette, Jaquillard, Lucie, Karsisiotis, Andreas I., Saab, Fabienne, Jouvensal, Laurence, Brans, Alain, Delmas, Agnès F., Schoentgen, Françoise, Cadene, Martine, Damblon, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338619/ https://www.ncbi.nlm.nih.gov/pubmed/22558375 http://dx.doi.org/10.1371/journal.pone.0036187 |
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