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Ligand Binding Study of Human PEBP1/RKIP: Interaction with Nucleotides and Raf-1 Peptides Evidenced by NMR and Mass Spectrometry

BACKGROUND: Human Phosphatidylethanolamine binding protein 1 (hPEBP1) also known as Raf kinase inhibitory protein (RKIP), affects various cellular processes, and is implicated in metastasis formation and Alzheimer's disease. Human PEBP1 has also been shown to inhibit the Raf/MEK/ERK pathway. Nu...

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Detalles Bibliográficos
Autores principales:	Tavel, Laurette, Jaquillard, Lucie, Karsisiotis, Andreas I., Saab, Fabienne, Jouvensal, Laurence, Brans, Alain, Delmas, Agnès F., Schoentgen, Françoise, Cadene, Martine, Damblon, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338619/ https://www.ncbi.nlm.nih.gov/pubmed/22558375 http://dx.doi.org/10.1371/journal.pone.0036187

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