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A Novel Inhibitor of Human La Protein with Anti-HBV Activity Discovered by Structure-Based Virtual Screening and In Vitro Evaluation

BACKGROUND: Over 350 million people worldwide are infected with hepatitis B virus (HBV), a major cause of liver failure and hepatocellular carcinoma. Current therapeutic agents are highly effective, but are also associated with development of viral resistance. Therefore, strategies for identifying o...

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Detalles Bibliográficos
Autores principales:	Tang, Jing, Huang, Zhi-Min, Chen, Ying-Yi, Zhang, Zhao-Hui, Liu, Gao-Lin, Zhang, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338670/ https://www.ncbi.nlm.nih.gov/pubmed/22558448 http://dx.doi.org/10.1371/journal.pone.0036363

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