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A Functional Variant of the Dimethylarginine Dimethylaminohydrolase-2 Gene Is Associated with Insulin Sensitivity

BACKGROUND: Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of endothelial nitric oxide synthase, which was associated with insulin resistance. Dimethylarginine dimethylaminohydrolase (DDAH) is the major determinant of plasma ADMA. Examining data from the DIAGRAM+ (Diabetes Genetics Re...

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Detalles Bibliográficos
Autores principales:	Andreozzi, Francesco, Presta, Ivan, Mannino, Gaia Chiara, Scarpelli, Daniela, Di Silvestre, Sara, Di Pietro, Natalia, Succurro, Elena, Sciacqua, Angela, Pandolfi, Assunta, Consoli, Agostino, Hribal, Marta Letizia, Perticone, Francesco, Sesti, Giorgio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338696/ https://www.ncbi.nlm.nih.gov/pubmed/22558392 http://dx.doi.org/10.1371/journal.pone.0036224

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