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A Stochastic Markov Chain Model to Describe Lung Cancer Growth and Metastasis
A stochastic Markov chain model for metastatic progression is developed for primary lung cancer based on a network construction of metastatic sites with dynamics modeled as an ensemble of random walkers on the network. We calculate a transition matrix, with entries (transition probabilities) interpr...
Autores principales: | Newton, Paul K., Mason, Jeremy, Bethel, Kelly, Bazhenova, Lyudmila A., Nieva, Jorge, Kuhn, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338733/ https://www.ncbi.nlm.nih.gov/pubmed/22558094 http://dx.doi.org/10.1371/journal.pone.0034637 |
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