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Arsenic Induces Functional Re-Expression of Estrogen Receptor α by Demethylation of DNA in Estrogen Receptor-Negative Human Breast Cancer

Estrogen receptor α (ERα) is a marker predictive for response of breast cancers to endocrine therapy. About 30% of breast cancers, however, are hormone- independent because of lack of ERα expression. New strategies are needed for re-expression of ERα and sensitization of ER-negative breast cancer ce...

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Detalles Bibliográficos
Autores principales: Du, Juan, Zhou, Nannan, Liu, Hongxia, Jiang, Fei, Wang, Yubang, Hu, Chunyan, Qi, Hong, Zhong, Caiyun, Wang, Xinru, Li, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338760/
https://www.ncbi.nlm.nih.gov/pubmed/22558281
http://dx.doi.org/10.1371/journal.pone.0035957