Neuropathology in Mouse Models of Mucopolysaccharidosis Type I, IIIA and IIIB

Mucopolysaccharide diseases (MPS) are caused by deficiency of glycosaminoglycan (GAG) degrading enzymes, leading to GAG accumulation. Neurodegenerative MPS diseases exhibit cognitive decline, behavioural problems and shortened lifespan. We have characterised neuropathological changes in mouse models...

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Detalles Bibliográficos
Autores principales: Wilkinson, Fiona L., Holley, Rebecca J., Langford-Smith, Kia J., Badrinath, Soumya, Liao, Aiyin, Langford-Smith, Alex, Cooper, Jonathan D., Jones, Simon A., Wraith, J. Ed, Wynn, Rob F., Merry, Catherine L. R., Bigger, Brian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338781/
https://www.ncbi.nlm.nih.gov/pubmed/22558223
http://dx.doi.org/10.1371/journal.pone.0035787

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