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CRISPR Interference Directs Strand Specific Spacer Acquisition

BACKGROUND: CRISPR/Cas is a widespread adaptive immune system in prokaryotes. This system integrates short stretches of DNA derived from invading nucleic acids into genomic CRISPR loci, which function as memory of previously encountered invaders. In Escherichia coli, transcripts of these loci are cl...

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Detalles Bibliográficos
Autores principales:	Swarts, Daan C., Mosterd, Cas, van Passel, Mark W. J., Brouns, Stan J. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338789/ https://www.ncbi.nlm.nih.gov/pubmed/22558257 http://dx.doi.org/10.1371/journal.pone.0035888

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