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Obstructed Labor and Caesarean Delivery: The Cost and Benefit of Surgical Intervention

BACKGROUND: Although advances in the reduction of maternal mortality have been made, up to 273,000 women will die this year from obstetric etiologies. Obstructed labor (OL), most commonly treated with Caesarean delivery, has been identified as a major contributor to global maternal morbidity and mor...

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Autores principales: Alkire, Blake C., Vincent, Jeffrey R., Burns, Christy Turlington, Metzler, Ian S., Farmer, Paul E., Meara, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338803/
https://www.ncbi.nlm.nih.gov/pubmed/22558089
http://dx.doi.org/10.1371/journal.pone.0034595
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author Alkire, Blake C.
Vincent, Jeffrey R.
Burns, Christy Turlington
Metzler, Ian S.
Farmer, Paul E.
Meara, John G.
author_facet Alkire, Blake C.
Vincent, Jeffrey R.
Burns, Christy Turlington
Metzler, Ian S.
Farmer, Paul E.
Meara, John G.
author_sort Alkire, Blake C.
collection PubMed
description BACKGROUND: Although advances in the reduction of maternal mortality have been made, up to 273,000 women will die this year from obstetric etiologies. Obstructed labor (OL), most commonly treated with Caesarean delivery, has been identified as a major contributor to global maternal morbidity and mortality. We used economic and epidemiological modeling to estimate the cost per disability-adjusted life-year (DALY) averted and benefit-cost ratio of treating OL with Caesarean delivery for 49 countries identified as providing an insufficient number of Caesarean deliveries to meet demand. METHODS AND FINDINGS: Using publicly available data and explicit economic assumptions, we estimated that the cost per DALY (3,0,0) averted for providing Caesarean delivery for OL ranged widely, from $251 per DALY averted in Madagascar to $3,462 in Oman. The median cost per DALY averted was $304. Benefit-cost ratios also varied, from 0.6 in Zimbabwe to 69.9 in Gabon. The median benefit-cost ratio calculated was 6.0. The main limitation of this study is an assumption that lack of surgical capacity is the main factor responsible for DALYs from OL. CONCLUSIONS: Using the World Health Organization's cost-effectiveness standards, investing in Caesarean delivery can be considered “highly cost-effective” for 48 of the 49 countries included in this study. Furthermore, in 46 of the 49 included countries, the benefit-cost ratio was greater than 1.0, implying that investment in Caesarean delivery is a viable economic proposition. While Caesarean delivery alone is not sufficient for combating OL, it is necessary, cost-effective by WHO standards, and ultimately economically favorable in the vast majority of countries included in this study.
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spelling pubmed-33388032012-05-03 Obstructed Labor and Caesarean Delivery: The Cost and Benefit of Surgical Intervention Alkire, Blake C. Vincent, Jeffrey R. Burns, Christy Turlington Metzler, Ian S. Farmer, Paul E. Meara, John G. PLoS One Research Article BACKGROUND: Although advances in the reduction of maternal mortality have been made, up to 273,000 women will die this year from obstetric etiologies. Obstructed labor (OL), most commonly treated with Caesarean delivery, has been identified as a major contributor to global maternal morbidity and mortality. We used economic and epidemiological modeling to estimate the cost per disability-adjusted life-year (DALY) averted and benefit-cost ratio of treating OL with Caesarean delivery for 49 countries identified as providing an insufficient number of Caesarean deliveries to meet demand. METHODS AND FINDINGS: Using publicly available data and explicit economic assumptions, we estimated that the cost per DALY (3,0,0) averted for providing Caesarean delivery for OL ranged widely, from $251 per DALY averted in Madagascar to $3,462 in Oman. The median cost per DALY averted was $304. Benefit-cost ratios also varied, from 0.6 in Zimbabwe to 69.9 in Gabon. The median benefit-cost ratio calculated was 6.0. The main limitation of this study is an assumption that lack of surgical capacity is the main factor responsible for DALYs from OL. CONCLUSIONS: Using the World Health Organization's cost-effectiveness standards, investing in Caesarean delivery can be considered “highly cost-effective” for 48 of the 49 countries included in this study. Furthermore, in 46 of the 49 included countries, the benefit-cost ratio was greater than 1.0, implying that investment in Caesarean delivery is a viable economic proposition. While Caesarean delivery alone is not sufficient for combating OL, it is necessary, cost-effective by WHO standards, and ultimately economically favorable in the vast majority of countries included in this study. Public Library of Science 2012-04-25 /pmc/articles/PMC3338803/ /pubmed/22558089 http://dx.doi.org/10.1371/journal.pone.0034595 Text en Alkire et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Alkire, Blake C.
Vincent, Jeffrey R.
Burns, Christy Turlington
Metzler, Ian S.
Farmer, Paul E.
Meara, John G.
Obstructed Labor and Caesarean Delivery: The Cost and Benefit of Surgical Intervention
title Obstructed Labor and Caesarean Delivery: The Cost and Benefit of Surgical Intervention
title_full Obstructed Labor and Caesarean Delivery: The Cost and Benefit of Surgical Intervention
title_fullStr Obstructed Labor and Caesarean Delivery: The Cost and Benefit of Surgical Intervention
title_full_unstemmed Obstructed Labor and Caesarean Delivery: The Cost and Benefit of Surgical Intervention
title_short Obstructed Labor and Caesarean Delivery: The Cost and Benefit of Surgical Intervention
title_sort obstructed labor and caesarean delivery: the cost and benefit of surgical intervention
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338803/
https://www.ncbi.nlm.nih.gov/pubmed/22558089
http://dx.doi.org/10.1371/journal.pone.0034595
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