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Targeted Delivery of Chemotherapy Agents Using a Liver Cancer-Specific Aptamer

BACKGROUND: Using antibody/aptamer-drug conjugates can be a promising method for decreasing toxicity, while increasing the efficiency of chemotherapy. METHODOLOGY/PRINCIPAL FINDINGS: In this study, the antitumor agent Doxorubicin (Dox) was incorporated into the modified DNA aptamer TLS11a-GC, which...

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Detalles Bibliográficos
Autores principales:	Meng, Ling, Yang, Liu, Zhao, Xiangxuan, Zhang, Lucy, Zhu, Haizhen, Liu, Chen, Tan, Weihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338807/ https://www.ncbi.nlm.nih.gov/pubmed/22558072 http://dx.doi.org/10.1371/journal.pone.0033434

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