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Characterization of Cyclin E Expression in Multiple Myeloma and Its Functional Role in Seliciclib-Induced Apoptotic Cell Death
Multiple Myeloma (MM) is a lymphatic neoplasm characterized by clonal proliferation of malignant plasma cell that eventually develops resistance to chemotherapy. Drug resistance, differentiation block and increased survival of the MM tumor cells result from high genomic instability. Chromosomal tran...
Autores principales: | Josefsberg Ben-Yehoshua, Liat, Beider, Katia, Shimoni, Avichai, Ostrovsky, Olga, Samookh, Michal, Peled, Amnon, Nagler, Arnon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338814/ https://www.ncbi.nlm.nih.gov/pubmed/22558078 http://dx.doi.org/10.1371/journal.pone.0033856 |
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