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The anti-Shine-Dalgarno sequence drives translational pausing and codon choice in bacteria

Protein synthesis by ribosomes takes place on a linear substrate but at variable speeds. Transient pausing of ribosomes can impact a variety of co-translational processes, including protein targeting and folding(1). These pauses are influenced by the sequence of the mRNA(2). Thus redundancy in the g...

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Detalles Bibliográficos
Autores principales: Li, Gene-Wei, Oh, Eugene, Weissman, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338875/
https://www.ncbi.nlm.nih.gov/pubmed/22456704
http://dx.doi.org/10.1038/nature10965