A vaccine targeting angiomotin induces an antibody response which alters tumor vessel permeability and hampers the growth of established tumors

Angiomotin (Amot) is one of several identified angiostatin receptors expressed by the endothelia of angiogenic tissues. We have shown that a DNA vaccine targeting Amot overcome immune tolerance and induce an antibody response that hampers the progression of incipient tumors. Following our observatio...

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Detalles Bibliográficos
Autores principales: Arigoni, Maddalena, Barutello, Giuseppina, Lanzardo, Stefania, Longo, Dario, Aime, Silvio, Curcio, Claudia, Iezzi, Manuela, Zheng, Yujuan, Barkefors, Irmeli, Holmgren, Lars, Cavallo, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338916/
https://www.ncbi.nlm.nih.gov/pubmed/22426512
http://dx.doi.org/10.1007/s10456-012-9263-3

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