Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab

Pharmacological inhibition of VEGF-A has proven to be effective in inhibiting angiogenesis and vascular leak associated with cancers and various eye diseases. However, little information is currently available on the binding kinetics and relative biological activity of various VEGF inhibitors. There...

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Detalles Bibliográficos
Autores principales: Papadopoulos, Nicholas, Martin, Joel, Ruan, Qin, Rafique, Ashique, Rosconi, Michael P., Shi, Ergang, Pyles, Erica A., Yancopoulos, George D., Stahl, Neil, Wiegand, Stanley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338918/
https://www.ncbi.nlm.nih.gov/pubmed/22302382
http://dx.doi.org/10.1007/s10456-011-9249-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338918/
https://www.ncbi.nlm.nih.gov/pubmed/22302382
http://dx.doi.org/10.1007/s10456-011-9249-6

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