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Effects of Nerve Growth Factor and Nitric Oxide Synthase Inhibitors on Amyloid Precursor Protein mRNA Levels and Protein Stability

We determined previously that nitric oxide (NO) modulates the nerve growth factor (NGF)-mediated increases in amyloid precursor protein (APP) levels in PC12 cells. To elucidate potential mechanisms, the effects of NGF and NO synthase (NOS) inhibitors on APP mRNA levels and protein stability were eva...

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Detalles Bibliográficos
Autores principales:	MacKinnon, Janet C, Huether, Patricia, Kalisch, Bettina E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Open 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339428/ https://www.ncbi.nlm.nih.gov/pubmed/22550546 http://dx.doi.org/10.2174/1874091X01206010031

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