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Targeting the IGF-1R signaling and mechanisms for epigenetic gene silencing in human multiple myeloma
Multiple myeloma (MM) is a B cell malignancy characterized by the expansion of clonal plasmablast/plasma cells within the bone-marrow. It is well established that the bone-marrow microenvironment has a pivotal role in providing critical cytokines and cell–cell interactions to support the growth and...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Informa Healthcare
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339548/ https://www.ncbi.nlm.nih.gov/pubmed/22348393 http://dx.doi.org/10.3109/03009734.2012.659293 |