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Complex effects of flavopiridol on the expression of primary response genes

BACKGROUND: The Positive Transcription Elongation Factor b (P-TEFb) is a complex of Cyclin Dependent Kinase 9 (CDK9) with either cyclins T1, T2 or K. The complex phosphorylates the C-Terminal Domain of RNA polymerase II (RNAPII) and negative elongation factors, stimulating productive elongation by R...

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Detalles Bibliográficos
Autores principales:	Keskin, Havva, Garriga, Judit, Georlette, Daphne, Graña, Xavier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339560/ https://www.ncbi.nlm.nih.gov/pubmed/22458775 http://dx.doi.org/10.1186/1747-1028-7-11

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