Cargando…
ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes
An indolent non-healing wound and insulin and/or insulin-like growth factor (IGF1) resistance are cardinal features of diabetes, inflammation and hypercortisolemia. Little is known about why these phenomena occur in so many contexts. Do the various triggers that induce insulin and/or IGF1 resistance...
Autores principales: | Bitar, Milad S., Al-Mulla, Fahd |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339831/ https://www.ncbi.nlm.nih.gov/pubmed/22362362 http://dx.doi.org/10.1242/dmm.007872 |
Ejemplares similares
-
Upregulation of CREM/ICER suppresses wound endothelial CRE-HIF-1α-VEGF-dependent signaling and impairs angiogenesis in type 2 diabetes
por: Bitar, Milad S., et al.
Publicado: (2015) -
A New Model for Raf Kinase Inhibitory Protein Induced Chemotherapeutic Resistance
por: Al-Mulla, Fahd, et al.
Publicado: (2012) -
The GSK-3β/Fyn/Nrf2 pathway in fibroblasts and wounds of type 2 diabetes: On the road to an evidence-based therapy of non-healing wounds
por: Bitar, Milad S.
Publicado: (2012) -
Functionally-focused algorithmic analysis of high resolution microarray-CGH genomic landscapes demonstrates comparable genomic copy number aberrations in MSI and MSS sporadic colorectal cancer
por: Ali, Hamad, et al.
Publicado: (2017) -
Alpha-Arbutin Promotes Wound Healing by Lowering ROS and Upregulating Insulin/IGF-1 Pathway in Human Dermal Fibroblast
por: Polouliakh, Natalia, et al.
Publicado: (2020)