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Effects of Ethanol and Acetaldehyde on Tight Junction Integrity: In Vitro Study in a Three Dimensional Intestinal Epithelial Cell Culture Model

BACKGROUND: Intestinal barrier dysfunction and translocation of endotoxins are involved in the pathogenesis of alcoholic liver disease. Exposure to ethanol and its metabolite, acetaldehyde at relatively high concentrations have been shown to disrupt intestinal epithelial tight junctions in the conve...

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Detalles Bibliográficos
Autores principales:	Elamin, Elhaseen, Jonkers, Daisy, Juuti-Uusitalo, Kati, van IJzendoorn, Sven, Troost, Freddy, Duimel, Hans, Broers, Jos, Verheyen, Fons, Dekker, Jan, Masclee, Ad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339854/ https://www.ncbi.nlm.nih.gov/pubmed/22563376 http://dx.doi.org/10.1371/journal.pone.0035008

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