Allele-specific Differences in Activity of a Novel Cannabinoid Receptor 1 (CNR1) Gene Intronic Enhancer in Hypothalamus, Dorsal Root Ganglia, and Hippocampus

Polymorphisms within intron 2 of the CNR1 gene, which encodes cannabinoid receptor 1 (CB(1)), have been associated with addiction, obesity, and brain volume deficits. We used comparative genomics to identify a polymorphic (rs9444584-C/T) sequence (ECR1) in intron 2 of the CNR1 gene that had been con...

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Detalles Bibliográficos
Autores principales: Nicoll, Gemma, Davidson, Scott, Shanley, Lynne, Hing, Ben, Lear, Marissa, McGuffin, Peter, Ross, Ruth, MacKenzie, Alasdair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Neurobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339935/
https://www.ncbi.nlm.nih.gov/pubmed/22362764
http://dx.doi.org/10.1074/jbc.M111.336750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339935/
https://www.ncbi.nlm.nih.gov/pubmed/22362764
http://dx.doi.org/10.1074/jbc.M111.336750

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