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Stability and microbiological properties of a new formulation of epoprostenol sodium when reconstituted and diluted

PURPOSE: Epoprostenol, used for the treatment of pulmonary arterial hypertension (PAH), has a number of limitations related to its short half-life in aqueous solution. The aim of this study was to evaluate the stability and microbiological properties of a new formulation, namely epoprostenol sodium...

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Detalles Bibliográficos
Autores principales: Lambert, Olivier, Bandilla, Dirk, Iyer, Rupa, Witchey-Lakshmanan, Leonore, Palepu, Nagesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340107/
https://www.ncbi.nlm.nih.gov/pubmed/22563237
http://dx.doi.org/10.2147/DDDT.S29916