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Protein Implicated in Nonsyndromic Mental Retardation Regulates Protein Kinase A (PKA) Activity

Mutation of the coiled-coil and C2 domain-containing 1A (CC2D1A) gene, which encodes a C2 domain and DM14 domain-containing protein, has been linked to severe autosomal recessive nonsyndromic mental retardation. Using a mouse model that produces a truncated form of CC2D1A that lacks the C2 domain an...

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Detalles Bibliográficos
Autores principales:	Al-Tawashi, Azza, Jung, Sung Yun, Liu, Dou, Su, Bing, Qin, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2012
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340277/ https://www.ncbi.nlm.nih.gov/pubmed/22375002 http://dx.doi.org/10.1074/jbc.M111.261875

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