Structural Basis for the Regulation of Protein Kinase A by Activation Loop Phosphorylation

The catalytic subunit of cAMP-dependent protein kinase (PKA) is a member of the AGC group of protein kinases. Whereas PKA has served as a structural model for the protein kinase superfamily, all previous structures of the catalytic subunit contain a phosphorylated activation loop. To understand the...

Descripción completa

Detalles Bibliográficos
Autores principales: Steichen, Jon M., Kuchinskas, Michael, Keshwani, Malik M., Yang, Jie, Adams, Joseph A., Taylor, Susan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340281/
https://www.ncbi.nlm.nih.gov/pubmed/22334660
http://dx.doi.org/10.1074/jbc.M111.335091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340281/
https://www.ncbi.nlm.nih.gov/pubmed/22334660
http://dx.doi.org/10.1074/jbc.M111.335091

Ejemplares similares