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Novel ATP-Independent RNA Annealing Activity of the Dengue Virus NS3 Helicase

The flavivirus nonstructural protein 3 (NS3) bears multiple enzymatic activities and represents an attractive target for antiviral intervention. NS3 contains the viral serine protease at the N-terminus and ATPase, RTPase, and helicase activities at the C-terminus. These activities are essential for...

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Detalles Bibliográficos
Autores principales:	Gebhard, Leopoldo G., Kaufman, Sergio B., Gamarnik, Andrea V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340334/ https://www.ncbi.nlm.nih.gov/pubmed/22558403 http://dx.doi.org/10.1371/journal.pone.0036244

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