Cathepsin S Deficiency Results in Abnormal Accumulation of Autophagosomes in Macrophages and Enhances Ang II–Induced Cardiac Inflammation

BACKGROUND: Cathepsin S (Cat S) is overexpressed in human atherosclerotic and aneurysmal tissues and may contributes to degradation of extracellular matrix, especially elastin, in inflammatory diseases. We aimed to define the role of Cat S in cardiac inflammation and fibrosis induced by angiotensin...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Lili, Li, Yulin, Jia, Lixin, Qin, Yanwen, Qi, Guanming, Cheng, Jizhong, Qi, Yongfen, Li, Huihua, Du, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340377/
https://www.ncbi.nlm.nih.gov/pubmed/22558139
http://dx.doi.org/10.1371/journal.pone.0035315

Ejemplares similares

Ejemplares similares