Synthesis and Evaluation of a Series of 2-Substituted-5-Thiopropylpiperazine (Piperidine)-1,3,4-Oxadiazoles Derivatives as Atypical Antipsychotics

BACKGROUND: It is important to develop novel antipsychotics that can effectively treat schizophrenia with minor side-effects. The aim of our work is to develop novel antipsychotics that act on dopamine D(2) and D(3), serotonin 5-HT(1A) and 5-HT(2A) receptors with low affinity for the serotonin 5-HT(...

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Detalles Bibliográficos
Autores principales: Chen, Yin, Xu, Xiangqing, Liu, Xin, Yu, Minquan, Liu, Bi-Feng, Zhang, Guisen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340383/
https://www.ncbi.nlm.nih.gov/pubmed/22558126
http://dx.doi.org/10.1371/journal.pone.0035186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340383/
https://www.ncbi.nlm.nih.gov/pubmed/22558126
http://dx.doi.org/10.1371/journal.pone.0035186

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