Influenza and SARS-Coronavirus Activating Proteases TMPRSS2 and HAT Are Expressed at Multiple Sites in Human Respiratory and Gastrointestinal Tracts

The type II transmembrane serine proteases TMPRSS2 and HAT activate influenza viruses and the SARS-coronavirus (TMPRSS2) in cell culture and may play an important role in viral spread and pathogenesis in the infected host. However, it is at present largely unclear to what extent these proteases are...

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Detalles Bibliográficos
Autores principales: Bertram, Stephanie, Heurich, Adeline, Lavender, Hayley, Gierer, Stefanie, Danisch, Simon, Perin, Paula, Lucas, Jared M., Nelson, Peter S., Pöhlmann, Stefan, Soilleux, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340400/
https://www.ncbi.nlm.nih.gov/pubmed/22558251
http://dx.doi.org/10.1371/journal.pone.0035876

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