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Interleukin-1β and transforming growth factor-β cooperate to induce neurosphere formation and increase tumorigenicity of adherent LN-229 glioma cells
INTRODUCTION: Glioma stem cells (GSCs) have the property of self-renewal and appear to be a driving force for the initiation and recurrence of gliomas. We recently found that the human tumorigenic LN-229 glioma cell line failed to form neurospheres in serum-free conditions and generated mostly small...
Autores principales: | Wang, Lei, Liu, Ziyan, Balivada, Sivasai, Shrestha, Tej, Bossmann, Stefan, Pyle, Marla, Pappan, Loretta, Shi, Jishu, Troyer, Deryl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340549/ https://www.ncbi.nlm.nih.gov/pubmed/22330721 http://dx.doi.org/10.1186/scrt96 |
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